The scientific approaches in the Institute directed toward the understanding and treatment of cancer are divided into eight major fields with Field Coordinator appointed to organize and develop the scientific disciplines. The eight fields of scientific endeavor are: Molecular Biology, Cell Surfaces, Viral Oncology, Immunobiology, Cancer Therapy, Human Cancer, Aging and Cancer and Biomedical Communications. The basic physical and chemical structure of normal and cancer cells will be further explored. The development of cellular and macromolecular engineering to correct defects of immunologic function will be continued. Studies on the control of cell proliferation, initiation and management of differentiation, the nature of cell-to-cell interactions and cell-to-cell communication as integral parts of the immune responses will be vigorously pursued. Our scientists will continue to explore the possibility of a link between viruses and human cancer. Viral oncologists will try to discover how the RNA viruses work that participate in causing most, if not all, of the cancers in mice. Especially important seems to be the interaction of these viruses through the special genetic makeup of the individual host. We shall continue to investigate how viruses control the function of the host's informational system.